People in the Computational and Molecular Population Genetics (CMPG) lab use molecular techniques, theoretical developments, and computer simulations to reconstruct the demographic history of populations and species from genetic data, and to test between alternative evolutionary scenarios.
Lab picture from January 2016: from left to right: Stephan Peischl, Andy Foote, Lars Bosshard, Vitor Sousa, Susanne Tellenbach, Isabelle Dupanloup Duperret, Matteo Tomasini, Miriam Zemanova, Joana Meier, Laurent Excoffier, Gerald Heckel, Alexandre Gouy, Moritz Saxenhofer, Isabel Alves, Adrien Foucal, Cindy Gidoin, David Marques, Anna Sapfo-Malaspinas, Natalia Zajac
We explore the genomic diversity of voles and humans in order to discover which genes have recently responded to selection, for instance to adapt to new environments.
We are also interested in quantifying the effect of range expansions and colonisation processes on genetic diversity, since these demographic events can lead to molecular signatures resembling those of selection.
We also develop and maintain computer programs to study and simulate the genetic diversity of populations, infer demographic parameters under complex scenarios, and detect loci under selection from genome scan.
The CMPG lab is affiliated to the Swiss Institute of Bioinformatics.